In the nutraceuticals field of research, the biochemical molecule NAD+, or Nicotinamide Adenine Dinucleotide, has been garnering a lot of attention for its effects in boosting metabolism, anti aging, and promoting longevity and disease prevention.
What is NAD+?
As one of the most crucial molecules in your body, NAD+ participates in 3 incredibly vital processes:
Generating energy - NAD+ works with the mitochondria to ensure your cells are fueled and operating efficiently (1)
Protecting DNA transcription - NAD+ is directly involved in the specific transcription networks that help cells with gene expression (2)
Regulating metabolism - NAD+ also influences the circadian rhythm, immune enzyme activity, and disease control
Think of NAD+ as a taxi that transports electrons between molecules in the cell so that chemical reactions can happen. These reactions are what amount to life-giving pathways and functions of the metabolism.
In other words, insufficient NAD+ levels can potentially reduce lifespan, accelerate aging, increase risk of neurodegenerative disorders, and affect heart function.
NAD+ and Aging
Studies have shown that NAD+ levels reduce with age, which may give rise to cardiovascular and neurological conditions in older populations.
Although more human tests are needed, the research conducted so far on animals, including mice, have concluded that replenishing NAD+ can improve fitness levels (3) and muscular retention (3), lengthen healthspan and lifespan (4).
How do we boost NAD+ levels?
There are a few strategies to naturally regulate and enhance NAD+ levels:
Studies have shown that regular fasting, exercise, and scenarios of caloric deficit are usually associated with increased NAD+ (5)
Avoid prolonged high fat diets as the body will initially compensate with increased NAD+ levels when you switch to high fat diets, but eventually those levels drop and cause functional damage (5)
Consume foods with the dietary precursors of NAD+, ie. NMN (Nicotinamide Mononucleotide) and NR (Nicotinamide Riboside), so that your body can synthesize NAD+ as needed
NMN rich foods include green vegetables, such as broccoli, cabbage, cucumber, as well as edamame.
NR rich foods are those that contain Vitamin B3, which include cow’s dairy and brewer’s yeast.(6)
R’s KOSO and NMN
R’s KOSO is a fermented beverage that is made with over 100 different plant foods, including the green vegetables that contain NMN as well as mushrooms and whole grains, which are associated with promoting NAD+ production in the body.
Consuming Koso could be an easy and tasty way to help your body produce adequate NAD+ to support anti-aging, anti-disease functions.
Keren Chen | CBT Nutritionist
Podcast - https://open.spotify.com/show/4FF59S3